The Trans-Allegheny Lunatic Asylum was a psychiatric hospital located in Weston, West Virginia and known by other names such as West Virginia Hospital for the Insane and Weston State Hospital. The asylum was open to patients from October 1864 until May 1994. After its closure, patients were transitioned to the new William R. Sharpe, Jr. Hospital in Weston, named after William R. Sharpe Jr., a member of the West Virginia Senate. The hospital reopened as a tourist location in March 2008.